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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
23.33
Human Site:
T166
Identified Species:
32.08
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
T166
K
K
D
V
I
E
L
T
D
D
S
F
D
K
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
T250
K
K
D
V
I
E
L
T
D
D
S
F
D
E
N
Dog
Lupus familis
XP_532876
440
48280
T166
K
K
D
V
I
E
L
T
D
D
S
F
D
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
T166
K
K
D
V
V
E
L
T
D
D
T
F
D
K
N
Rat
Rattus norvegicus
Q63081
440
48155
T166
K
K
D
V
V
E
L
T
D
D
T
F
D
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
A162
V
W
L
V
E
F
Y
A
P
W
C
G
H
C
K
Chicken
Gallus gallus
Q8JG64
505
56163
Y166
R
D
A
S
G
D
A
Y
S
E
F
M
K
A
A
Frog
Xenopus laevis
NP_001086643
442
47765
E166
G
S
K
K
D
V
I
E
L
T
D
D
T
F
D
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
T166
K
K
D
V
V
E
L
T
D
D
N
F
D
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
F206
K
D
N
G
V
V
L
F
K
P
F
D
D
K
K
Honey Bee
Apis mellifera
XP_395981
427
47177
I162
T
D
D
T
F
D
N
I
V
M
N
S
D
D
M
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
E165
G
G
G
G
S
G
N
E
V
V
E
L
T
D
A
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
G154
G
S
G
S
G
G
S
G
S
G
G
S
G
G
K
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
E159
S
K
E
L
W
I
V
E
F
F
A
P
W
C
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
P116
E
P
Q
K
Y
E
G
P
R
N
A
E
A
L
A
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
A72
L
S
S
T
F
R
K
A
A
K
R
L
D
G
V
Red Bread Mold
Neurospora crassa
Q92249
369
39263
N123
R
D
L
D
S
L
S
N
F
I
A
E
K
T
G
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
93.3
100
N.A.
86.6
86.6
N.A.
6.6
0
0
73.3
N.A.
26.6
13.3
0
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
20
13.3
93.3
N.A.
40
26.6
0
0
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
33.3
N.A.
N.A.
26.6
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
0
6
12
6
0
18
0
6
6
18
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
0
0
12
0
% C
% Asp:
0
24
42
6
6
12
0
0
36
36
6
12
53
12
6
% D
% Glu:
6
0
6
0
6
42
0
18
0
6
6
12
0
6
0
% E
% Phe:
0
0
0
0
12
6
0
6
12
6
12
36
0
6
0
% F
% Gly:
18
6
12
12
12
12
6
6
0
6
6
6
6
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
0
0
0
0
18
6
6
6
0
6
0
0
0
0
0
% I
% Lys:
42
42
6
12
0
0
6
0
6
6
0
0
12
30
18
% K
% Leu:
6
0
12
6
0
6
42
0
6
0
0
12
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
6
0
0
6
% M
% Asn:
0
0
6
0
0
0
12
6
0
6
12
0
0
0
30
% N
% Pro:
0
6
0
0
0
0
0
6
6
6
0
6
0
0
0
% P
% Gln:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
6
0
0
6
0
6
0
0
6
0
% R
% Ser:
6
18
6
12
12
0
12
0
12
0
18
12
0
0
0
% S
% Thr:
6
0
0
12
0
0
0
36
0
6
12
0
12
6
6
% T
% Val:
6
0
0
42
24
12
6
0
12
6
0
0
0
0
6
% V
% Trp:
0
6
0
0
6
0
0
0
0
6
0
0
6
0
0
% W
% Tyr:
0
0
0
0
6
0
6
6
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _